Why Pharmaceutical Substances?

The structure-searchable resource is an ideal tool for researchers, process chemists and for teaching in the field of medicinal and pharmaceutical chemistry.

Essential for research

  • Full synthetic route for the industrial manufacture of each drug elucidated from the patent literature
  • Unique source of reactions that perform on an industrial scale
  • Overview of the pharmaceutical industry from a synthetic chemist's perspective
  • Insights into a therapeutic area and chemically related substances

Essential for business development

  • First determination of the market size and competition for an API - essential for development of new and generic pharmaceuticals
  • Source of markets for synthesis intermediates, ingredients and enzymes
  • Patent information including approval date and expiration
  • Comprehensive coverage of older APIs and substances approved worldwide
  • Merger and acquisition tracking ensuring that vendor information is up-to-date in a rapidly changing industry

Essential for teaching

  • Capability to search for marketed drugs relating to a structure or reaction
  • A rapid overview of a therapeutic area or chemically related substances
  • Industrial synthetic routes discerned from complex patent descriptions
  • Insights into industrial processes and toxicity issues
  • Commercial information such as trade names and vendors/manufacturers for six world markets
  • Concise records ideal for hand-outs and quick reference

“I love Kleemann/Engel [Pharmaceutical Substances] because it helps me prepare for classes, in particular on synthetic design. I don't only cover natural products but also multistep drug syntheses in these courses. It's also very useful for introductory classes in organic chemistry to illustrate, for instance, Friedel-Crafts reactions or Mannich reactions with concrete and important examples. Especially the premeds love it when I show an application in a drug synthesis.”

Prof. Dirk Trauner, New York University, New York, USA


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