News-Archive 2021

Cooperation brings together machine learning and expert human-curated data with unprecedented results in synthesis reaction planning

Electrosynthesis represents an increasingly viable platform for molecular synthesis; this volume presents the key concepts, strategies, and latest advances.

Mark Lautens will take over as Editor-in-Chief from Paul Knochel on January 1, 2022.

Prof. Hong-Li Bao, Fujian Institute of Research on the Structure of Matter (P. R. of China), joins the Editorial Board of SYNTHESIS.

This volume describes the most useful click transformations, and their applications in the chemical, biological, and materials sciences.

T. Kurahashi and S. Matsubara show a new synthetic route to (trifluoromethyl)quinolines.

Xi-Sheng Wang describes the cobalt-catalyzed hydrocyanation of monofluoroalkenes.

Narihito Ogawa reports on the synthesis of (–)-heliannuol E by selective propargyl substitution.

Methods for the Synthesis and Modification of 1,4-Dioxanes Compiled and Reviewed for SOS

Nobel Prize in Chemistry 2021 has been awarded to Benjamin List and David MacMillan.

From now on, Dr. Eduarda Silva, University of Porto (Portugal), takes care of Crowd Review for SynOpen.

Key Synthetic Routes to Piperazine Structures Comprehensively Reviewed for SOS

John Keating beschreibt die Pd-katalysierte Synthese von Pyrazolo[3,4-b]pyridin-3-carboxamiden.

Yinan Zhang and Lihong Hu present an efficient route for the synthesis of (±)-epi-costunolide.

Put your knowledge of chemical names to the test!

New Science of Synthesis Review on Acyclic Geminal Bisperoxides

Anup Kumar Misra reports on the synthesis of an important pentasaccharide.

Jesper Kristensen describes an improved synthetic method for 25CN-NBOH.

The partnership aims at improving the prediction of chemical reaction results using artificial intelligence and synthesis data from Thieme's digital publication source for organic chemistry – Science of Synthesis.

Professor Jean-Marc Campagne is welcomed to the team!

Hokkaido University Researchers Review Borylative Ring Closure

Radical chemistry is undergoing a renaissance, both in the selective generation of organic radicals and in their use in organic synthetic reactions.

Josep Cornella reports on the introduction of tetra- and pentafluorosulfanyl groups into aryl compounds.

Eminent chemist and Science of Synthesis author Ei-ichi Negishi passed away on June 6th, 2021.

Professor Tim Donohoe joins the Science of Synthesis Editor Team.

Naoyuki Shimada describes the synthesis of various derived Weinreb amides.

Julian Garrec and Alexis Archambeau present the Pd-catalyzed synthesis of oxazocine scaffolds.

Recent developments in purine synthesis have been reviewed by Professor Stanislav Wnuk and colleagues.

Yukun Guan reports on the total synthesis of (+)-aphanorphine.

Raju Jannapu Reddy presents an efficient synthesis of allyl aryl sulfones.

Daniel Rampon describes the Ir(III)-catalyzed chalcogenylation of naphthalene derivatives.

James McNulty presents a catalytic, oxidative synthesis of olivetol and various derivatives.

Prof. Corinna Schindler, University of Michigan (USA), has joined the Editorial Board of SYNTHESIS.

Dr. Narendra Ambhaikar reviews recent synthetic routes to phenazine structures

Chen-Liang Deng describes the Ni-catalyzed intramolecular nucleophilic addition of aryl halides to aryl ketones.

Prof. Martin Oestreich, TU Berlin (Germany), joins the Editorial Board of SYNTHESIS.

Mohanad Shkoor synthesizes fluorenone-fused coumarins via DMPA catalysis.

Kazuyuki Sugita shows the stereoselective synthesis of the cotylenin A aglycone carbon skeleton.

Elizabeth Jarvo reports on a new method to synthesize fluorinated cyclopropanes.

A. Berkefeld and I. Fleischer present the Ni-H-catalyzed cleavage of allyl ethers.

Marcus Baumann describes the continuous photochemical synthesis of benzyne.

On December 18, 2020, the outstanding chemist and long-term SYNLETT and SYNFACTS Editor Victor Snieckus passed away at the age of 83.

M. Kanai and K. Oisaki for SYNTHESIS and P. Kraft, Q. Wang and S. Riniker for SYNLETT, together with their co-authors, are the recipients of the 2020 Best Paper Awards.

Jean-Marc Campagne and Renata Marcia de Figueiredo show the ring expansion of vinyl aziridines under mild conditions.

Professor Elena Fernández is the new volume editor for Boron Compounds.

Taleb H. Al-Tel presents a modular approach to constrained benzoxazepine and imidazopyrazine systems.

Franz Bracher describes a new, flexible route to N-aryl-1,2,3,4-tetrahydroisoquinolines.

X. Hong and S.-Q. Zhang developed a new SPMS descriptor for the featurization of van der Waals surface.

Francesco Secci presents a new synthetic method to construct indolyl cyclobutanones.

Dorota Gryko reports on the dicarbofunctionalization of bromoalkenes.