Chemoselective Activation of sp3 vs sp2 C–H Bonds with Pd(II)

Oxidative C–H activation is the most atom-economical process for the construction of carbon–carbon bonds. The ability of some metals, such as Pd catalysts, to insert selectively into C–H bonds has provided a host of new, useful methods for the synthesis of organic molecules. The group of Professor Marisa C. Kozlowski at the University of Pennsylvania (USA) has had an ongoing interest in oxidative C–H activation and recently presents their latest results in this area.

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