Synthesis of Nepetoidin B
Synthesis of Nepetoidin B: V. Timokhin, M. Regner, Y. Tsuji, J. Grabber, J. Ralph
Synlett 2018, DOI: 10.1055/s-0036-1591556
Nepetoidin B is a natural bis-catechol derivative that can be isolated in generally small amounts from different plants, including Salvia miltiorrhiza Bunge. Due to its bioactivity nepetoidin B has attracted significant interest for potential biomedical applications; however, its limited availability has hitherto hampered further studies on its properties. Recently, the group of Professor John Ralph from the University of Wisconsin, Madison (USA) has published a simple and short synthesis of this compound.