Aleksei Yevgen’evich Chichibabin and Pyridine Chemistry
This Name Reaction Biography highlights the influence of Aleksei Y. Chichibabin on pyridine chemistry.
The pyridine ring is viewed as a privileged structure in medicinal chemistry, and is well represented in modern pharmaceuticals, as illustrated by the antihistamine loratadine , the antiretroviral compound nevirapine, the acetylenic retinoid tazarotene (used to treat skin conditions such as psoriasis), and dihydropyridine calcium channel blockers (used to treat hypertension). In this sesquicentennial of the birth of the great pyridine chemist, Aleksei Yevgen’evich Chichibabin (1871–1945), it is appropriate that this name reaction biography focuses on pyridine and its analogues.
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