Metal-Catalyzed Cyclization Reactions
These two SOS volumes present the broad scope of metal-catalyzed reactions for the synthesis of cyclic compounds, from long-established methods to state-of-the-art approaches. The power of these reactions is highlighted by selected examples of application in natural product/drug synthesis.
Significant advances in metal-catalyzed reactions, especially cyclizations, have dramatically improved the efficiency of organic synthesis over the last three decades. To date, these transformations are widely used in the area of synthesis of both natural products and therapeutic agents. "Science of Synthesis: Metal-Catalyzed Cyclization Reactions" presents the most commonly used and significant metal-catalyzed reactions for modern organic synthesis. The basic principles, the current state of the art, scope, limitations, and mechanism of these reactions are also discussed. Typical examples of target synthesis are provided to help inspire further applications.
Volume 1 covers intramolecular coupling reactions (including Heck reactions), intramolecular allylations, and cyclopropane and cyclopropene ring openings. Also included are cyclization reactions of alkenes, alkynes, and allenes, cycloisomerizations, and intramolecular C—N and C—O bond formation.
Volume 2 covers epoxidations, aziridinations, cyclopropanations, and Pauson–Khand reactions, as well as a wide range of cycloaddition processes, radical cyclizations, and ring-closing metathesis.
Metal-Catalyzed Cyclization Reactions Volume 1
Metal-Catalyzed Cyclization Reactions Volume 2
Prof. Shengming Ma Volume Editor Shanghai Institute of Organic Chemistry, Shanghai, China
Prof. Shuanhu Gao Volume Editor East China Normal University, Shanghai, China
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