Fluorescently Labeled Amino Acids as Building Blocks for Bioactive Molecules
Michael Gütschow and Daniela Häußler designed fluorescently labeled amino acids as building blocks for bioactive molecules.
Fluorescently Labeled Amino Acids as Building Blocks for Bioactive Molecules: D. Häußler, M. Gütschow
Synthesis 2015, DOI: 10.1055/s-0035-1560361
Fluorescent peptides are essential probes in biomedical research for studying and visualizing a wide array of biological processes. Therefore, the design and synthesis of fluorescent amino acids represent a vibrant area of organic chemistry. Recently, the group of Professor Michael Gütschow from the University of Bonn (Germany) has reported the synthesis of a novel class of fluorescently labeled amino acids incorporating different fluorophores studying also their spectroscopic properties.
Professor Gütschow said: “Fluorescently labeled amino acids, addressing the blue-to-green region of the visible light spectrum are useful building blocks for the synthetic assembly of biologically active, fluorescent compounds.”