Iodide-Catalyzed Carbonylation–Benzylation of Benzyl Chlorides
Wei Han describes the iodide-catalyzed carbonylation–benzylation of benzyl chlorides.
Iodide-Catalyzed Carbonylation–Benzylation of Benzyl Chlorides with Potassium Aryltrifluoroborates under Ambient Pressure of Carbon Monoxide: W. Han, J. Chen, F. Jin, X. Yuan
Synlett 2017, DOI: 10.1055/s-0036-1591502
The carbonylative Suzuki tricomponent reaction is a powerful and versatile methodology for the synthesis of ketones; however, it normally requires the use of metal catalysts, which are often expensive, require carefully controlled conditions and are generally problematic environmentally. The group of Professor Wei Han from Nanjing Normal University (P. R. of China) has recently reported a new way to perform this carbonylative reaction by using a metal-catalyst-free procedure.