Current SynOpen Highlights
SynOpen is an international open access journal reporting current research results in chemical synthesis in full paper, letter and review format. We present you today a few new features:
- SynOpen generally uses Select Crowd Review for reviewing manuscripts
- Authors have the possibility to opt for double-blind review in connection with select crowd review.
- SynOpen offers now the option to submit Spotlights, which highlight the preparation and uses of selected reagents and methods in current research.
Please see the latest example:
Hedouin, Gaspard; Dherbassy, Quentin; Wencel-Delord, Joanna; Colobert, Françoise:
An Improvement of the Synthesis of (1R,2S,5R)-(–)-Menthyl (S)-p-Toluenesulfinate
If you are interested to submit a Spotlight, please first contact Editor-in-Chief Prof. Laurence M. Harwood.
Moreover, we recommed these two highlights:
Development of a Continuous Photochemical Benzyne-Forming Process
A continuous-flow process is presented that enables the safe generation and derivatization of benzyne under photochemical conditions. This is facilitated by a new high-power LED lamp emitting light at 365 nm. The resulting flow process effectively controls the release of gaseous by-products based on an adjustable backpressure regulator and delivers a series of heterocyclic products in a short residence time of 3 minutes. The robustness of this methodology is demonstrated for the rapid generation of benzotriazoles, 2H-indazoles and various furan-derived adducts, facilitating the preparation of these important heterocyclic scaffolds via a simple and readily scalable flow protocol.
Read the full article here.
4-Cyano-3-oxotetrahydrothiophene (c-THT): An Ideal Acrylonitrile Anion Equivalent
4-Cyano-3-oxotetrahydrothiophene (c-THT) has much more to offer than just a platform to various heterocyclic scaffolds. This solid, bench-stable and commercially available reagent can be readily transformed into thioglycolic acid and acrylonitrile upon simple addition of a hydroxide anion. This interesting feature enables its use as a particularly versatile acrylonitrile anion surrogate.
Read the full article here.
